Tag-arkiv: american journal of psychiatry

Behandling af behandlingsresistent OCD

Det Lundbeck udviklet Ebixa (Memantin) har ifølge et mindre forsøg beskrevet i American Journal of Psychiatry vist sig effektivt i behandling af behandlingsresistent OCD. Præparatet er oprindeligt udviklet til behandling af demens, men som så mange andre former for farmaka har det vist sin effektivitet på andre områder.
Er Ebixa en up-coming blockbuster for Lundbeck ?

Kilde: Memantine for Treatment-Resistant OCD, Am J Psychiatry 162:2191-a-2192, November 2005

Family Functioning of Children With OCD and Comorbid ADHD

New research:
Adaptive, Emotional, and Family Functioning of Children With Obsessive-Compulsive Disorder and Comorbid Attention Deficit Hyperactivity Disorder.

OBJECTIVE: The purpose of the study was to examine adaptive, emotional, and family functioning in a well-characterized group of children and adolescents with obsessive-compulsive disorder (OCD) and to evaluate the influence of comorbid attention deficit hyperactivity disorder (ADHD) on the levels of impairment in various functional domains.
RESULTS: The children with OCD only were more impaired than were unaffected comparison subjects in most areas of adaptive functioning and emotional adjustment. Children with OCD plus ADHD had additional difficulties in social functioning, school problems, and self-reported depression. Impairment in daily living skills, reduced number of activities, and self-reported anxiety were uniquely associated with the diagnosis of OCD. Family dysfunction was associated with ADHD but not with OCD. CONCLUSIONS: Children and adolescents with OCD are impaired in multiple domains of adaptive and emotional functioning. When comorbid ADHD is present, there is an additional burden on social, school, and family functioning.

Article from The American Journal of Psychiatry: 162:1125-1132, June 2005